LABORATORY OF GENE TECHNOLOGY

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I. HISTORY

In 2003, Hue University set up a Laboratory of Molecular Biotechnology, belong to the Center for Resources, Environment and Biotechnology (CREB), Hue University (located at 27 Phan Dinh Phung Str., Hue city).

In November 2007, the Institute of Resources, Environment and Biotechnology (IREB) was established based on the reorganization of CREB, Laboratory of Molecular Biotechnology became the Department of Applied DNA Technology.

In 2011, the department was renamed to the Department of Molecular Biology.

In April 2013, the Department was separated from IREB and belonged to Center for Scientific Incubation and Transfer (CSIT), Hue University.

In May 2014, the Institute of Biotechnology (HUIB) was re-established and the Department of Molecular Biology was re-established.

In April 2019, the department was renamed to Laboratory of Gene Technology.

II. STAFFS

Hoang Tan Quang, PhD
Head of laboratory
Phone: +84983735509
Email: htquang@hueuni.edu.vn

Tran Thuy Lan, MSc.
Researcher
Phone: +84934815251
Email: ttlan@hueuni.edu.vn

Pham Thi Diem Thi, MSc.
Researcher
Phone: +84983336019
Email: ptdiemthi@hueuni.edu.vn

Nguyen Minh Tri, MSc.
Researcher
Phone: +84347397570
Email: nguyenminhtri@hueuni.edu.vn

III. RESEARCH INTERESTS

  • Production of biological products using recombinant DNA technology for agriculture.
  • Gene expression regulation in plant and microorganism.
  • Biodiversity of valuable genetic resources.
  • Conservation and propagation of valuable medicine plants.
  • Production of bioactive compounds based on plant cells tissue culture.

IV. PUBLICATIONS

Projects

– Ministry of Education and Traning (2014-2016): Research on saponin production from Paris polyphylla Sm. cell suspension cultivation. PI. Hoang Tan Quang.

– Hue University (2018-2019): Research on in vitro propagation of Adenosma indianum (Lour.) Merr. PI. Hoang Tan Quang.

– Ministry of Education and Traning (2019-2020): Production of gypenoside from cell suspension culture of Gynostemma pentaphyllum (Thunb.) Makino. PI. Hoang Tan Quang.

International journal

  1. Nguyen Hoang Loc, Le My Tieu Ngoc, Hoang Tan Quang, Nguyen Duc Huy, Nguyen Ngoc Luong (2016) Cloning and expression of two genes coding endo-β-1,4-glucanases from Trichoderma asperellum PQ34 in Pichia pastoris. Chemical Papers 70(3): 284-293.
  2. Hoang Tan Quang, Cai Thi Quynh Thoa, Trinh Huu Tan, Nguyen Thanh Giang, Nguyen Duc Huy, Truong Thi Bich Phuong, Van Thi Yen (2016) Study on genetic diversity of Paris polyphylla population from Vietnam and China. Plant Cell Biotechnology and Molecular Biology 17(1&2): 57-63.
  3. Nguyễn Đức Huy, Nguyễn Thị Thanh Tiền, Lê Thị Huyền, Hoàng Tấn Quảng, Trương Quý Tùng, Nguyễn Ngọc Lương, Seung-Moon Park (2017) Screening and production of manganese peroxidase from Fusarium on residue materials. Mycobiology 45(1): 52-56.
  4. Quoc-Dung Tran, The Hung-Anh Mai, Tan-Quang Hoang, Van-Giang Tran, Thi Phuong-Anh Vu (2017) Genetic diversity of loach Misgurnus anguillicaudatus (Cantor, 1842) in Vietnam by randomly amplified polymorphic DNA analysis. Journal of Chemical, Biological and physical sciences 8(1): 106-119.
  5. Van-Thuan Nguyen, Van-Giang Tran, Tran-Trung Nguyen, Tan-Quang Hoang, Quoc-Dung Tran (2018) Genetic diversity of earthworm Amynthas rodericensis (Grube, 1879) (Clitellata: Megascolecidae) in Vietnam by randomly amplified polymorphic DNA analysis. Journal of Chemical, Biological and Physical Sciences. Section B 8(4): 870-883.
  6. Hoang Tan Quang, Bui Le Thanh Nhan, Tran Minh Duc, Tran Van Giang, Pham Thanh (2018) Study on genetic diversity of Curculigo orchioides Gaertn populations from Vietnam, an endangered medicinal herb. Plant cell biotechnology and molecular biology 19(7-8): 293-301.
  7. Dung Q. Tran, Thien V. Tran, Quang T. Hoang (2018). Genetic Relationship of Two Agamid Lizard Species in Vietnam by Random Amplified Polymorphic DNA Analysis. Life Science Journal 15(10): 36-42.
  8. Nguyen Quang Duc Tien, Le Quang Man, Ngo Thi Ly, Duong Thi Kim Chi, Tran Thuy Lan, Nguyen Xuan Huy (2019) Cloning, expression, and purification of truncated S1 epitope and peptide CT24 fusion protein of porcine epidemic diarrhea virus in Escherichia coli. Plant cell biotechnology and molecular biology 20(3-4): 112-118.
  9. Truong Thi Bich Phuong, Phan Thuy Truc Nhu, Lam Thi Ngoc Thuy, Tran Thuy Lan, Tran Quoc Dung, Hoang Tan Quang (2019) In vitro propagation of Adenosma indianum (Lour.) Merr. Plant Cell Biotechnology and Molecular Biology 20(5-6): 222-231.
  10. Truong Thi Phuong Lan, Nguyen Duc Huy, Nguyen Ngoc Luong, Hoang Tan Quang, Trinh Huu Tan, Le Thi Anh Thu, Nguyen Xuan Huy, Nguyen Hoang Loc (2019) Expression of elicitor-induced curcuminoid genes in cells of zedoary (Curcuma zedoaria Roscoe). Journal of Plant Biotechnology 46:172-179.
  11. Nguyen Hoang Loc, Nguyen Duc Huy, Hoang Tan Quang, Tran Thuy Lan, Tran Thi Thu Ha (2020) Characterisation and antifungal activity of extracellular chitinase from a biocontrol fungus, Trichoderma asperellum Mycology 11(1): 38-48, DOI: 10.1080/21501203.2019.1703839
  12. Nguyen Duc Huy, Le My Tieu Ngoc, Nguyen Hoang Loc, Tran Thuy Lan, Hoang Tan Quang, Tran Quoc Dung, Truong Thi Phuong Lan, Vu Duc Hoang, Nguyen Thi Dong Phuong (2020) Isolation of Weissella cibaria from Pacific white shrimp (Litopenaeus vannamei) gastrointestinal tract and evaluation of its pathogenic bacterial inhibition. Indian Journal of Science and Technology: 13(10), 1200-1212. DOI: 10.17485/ijst/2020/v013i10/149934.
  13. Hoang Tan Quang, Tran Thuy Lan, Truong Thi Hong Hai, Pham Thi Hai Yen, Tran Quang Khanh Van, Ho Thi Tung, Mac Nhu Binh, Nguyen Khoa Huy Son, Nguyen Quang Linh, Nguyen Duy Quynh Tram (2020) Genetic diversity and toxic genes analysis of Vibrio isolated from white leg shrimp and marine fishes cultured in Tam Giang lagoon in Thua Thien Hue province, Vietnam. Indian Journal of Science and Technology 13(13): 1412-1422. https://doi.org/10.17485/IJST/v13i13.161
  14. Hoang Tan Quang, Pham Thi Diem Thi, Tran Thuy Lan, Nguyen Duc Huy, Nguyen Duy Quynh Tram, Nguyen Thi Thu Lien (2020) Development of a diagnostic SCAR marker for Vibrio shilonii caused acute hepatopancreatic necrosis disease in whiteleg shrimp. Advancements in Life Sciences 7(4): 257-263.

Domestic journal

  1. Hoang Tan Quang, Trinh Huu Tan, Nguyen Thanh Giang, Nguyen Duc Huy, Truong Thi Phuong Lan (2016) Effects of methyl jasmonate on saponin accumulation in cultured suspension cells of Paris polyphylla. Proceeding of the 2nd national conference on biological research and teaching in Vietnam. 1176-1183
  2. Dang Thi Thanh Ha, Le Kim Tuan, Dinh Thi Kim Thien, Pham Thi Ngoc Lan, Hoang Tan Quang, Tran Thuy Lan, Nguyen Duc Huy (2018) Cloning and sequencing laccase 3 (Folac3) from Fusarium oxysporum. Journal of Sciences, Hue University 127(1C): 1-10.
  3. Hoang Tan Quang, Tran Thi Dieu, Le Thi Le Quyen, Pham Thi Diem Thi, Truong Thi Hong Hai, Tran Quoc Dung (2018) In vitro shoot regeneration of Adenosma indianum (Lour.) Merr. through callus induction. Journal of Sciences, Hue University 127(1C): 53-60.
  4. Hoang Tan Quang, Nguyen Thi Khanh Linh, Trinh Huu Tan, Dang Phuoc Hai, Nguyen Thi Thanh Huyen, Tran Quoc Dung (2018) Morphological characteristics and genetic diversity of Adenosma indianum (Lour.) Merr. populations in Quang Tri and Thua Thien Hue provinces. Proceeding of The National Conference of Biotechnology 2018: 1366-1371.
  5. Hoang Tan Quang, Le Pho Quynh Nhu, Nguyen Minh Tri, Le Thi Tuyet Nhan, Le Nhu Cuong, Truong Thi Hong Hai, Dang Ngoc Sang (2019) In vitro propagation of Gynostemma pentaphyllum (Thunb.) Makino via callus induction. Journal of Sciences, Hue University: Natural Sciences 128 (1E): 59-68.
  6. Nguyen Huu Nhan, Hoang Tan Quang, Nguyen Hoang Loc (2019) Effects of culture media on growth ability of Eurycoma longifolia Jack callus. Journal of Sciences, Hue University: Natural Sciences 128 (1E): 69-76.
  7. Nguyen Huu Nhan, Hoang Tan Quang, Nguyen Hoang Loc (2020) Effects of culture media and conditions on growth ability of Eurycoma longifolia Jack suspension cells. Journal of Sciences and Technology, Hue University of Sciences, Hue University 16(2): 155-166.
  8. Hoang Tan Quang, Tran Thuy Lan, Pham Thi Diem Thi, Le Thi Tuyet Nhan, Le My Tieu Ngoc, Nguyen Duy Quynh Tram, Nguyen Thi Thu Lien (2020) Screening and analysing toxic genes from Vibrio isolates causing acute hepatopancreatic necrosis disease in white-leg shrimp at Thua Thien Hue. Journal of Sciences, Hue University: Natural Sciences 129(1A): 115–123.
  9. Tran Quang Khanh Van, Pham Thi Hai Yen, Hoang Tan Quang, Ho Thi Tung, Nguyen Khoa Huy Son, Nguyen Quang Linh, Nguyen Duy Quynh Tram (2020). Evatuation the situation of acute hepatopancreaflc necrosis disease on white shrimp Litopenaeus vannamei in Thua Thien-Hue province. Journal of Agricultural and Rural development 1: 63-68.
  10. Hoang Tan Quang, Pham Thi Diem Thi, Tran Thuy Lan, Pham Thi Hai Yen, Tran Quang Khanh Van, Nguyen Duy Quynh Tram (2020) Development of a diagnostic SCAR marker for Vibrio vulnificus causing ulcerative disease in marine fishes in Thua Thien Hue. Journal of Sciences, Hue University: Natural Sciences 129(1C): 99-108.
  11. Hoang Tan Quang, Nguyen Dinh Khoa, Tran Thuy Lan, Pham Thi Diem Thi, Truong Thi Bich Phuong, Nguyen Duy Quynh Tram, Nguyen Thi Thu Lien (2020) Genetic diversity analysis of Vibrio species isolated from shrimp and fishes in Thua Thien Hue province, Vietnam. Proceeding of 2020 Vietnam National Conferrence on Biotechnology: 93-98.
  12. Bui Le Thanh Nhan, Nguyen Bao Hung, Nguyen Thi Thu Hien, Hoang Tan Quang, Truong Thi Bich Phuong (2020) Assesssing the lycorine content of Curculigo orchioides G by HPLC-FD. Proceeding of 2020 Vietnam National Conferrence on Biotechnology: 244-249.
  13. Tran Thi Ngoc Anh, Pham Thi Diem Thi, Tran Thuy Lan, Tran Quoc Dung, Nguyen Quang Hoang Vu, Truong Thi Bich Phuong, Hoang Tan Quang (2020) Affect of culture conditions on growth and accumulation of saponin RB1 IN Gynostemma pentaphyllum (Thunb.) Makino suspension cells. Proceeding of 2020 Vietnam National Conferrence on Biotechnology: 885-890.

V. SCIENTIFIC AWARDS

1. 2017 Co Do award in science and technology

Title: Development and application of recombinant microbial enzymes.

Author: Nguyen Hoang Loc, Do Thi Bich Thuy, Tran Thi Thu Ha, Hoang Tan Quang, Nguyen Duc Huy, Nguyen Bao Hung, Nguyen Thi Quy Hoa, Le My Tieu Ngoc, Nguyen Ngoc Luong

2Third award from ThuaThienHue contest on Science and Technology, 2018 

Title: Identification manganese peroxidase production fungi from Thua Thien Hue.

Author: Nguyen Duc Huy, Hoang Tan Quang, Tran Thuy Lan, Le Thi Dieu Huyen, Nguyen Thi Thanh Tuyen, Nguyen Thi Be.

 

English