{"id":7584,"date":"2020-03-31T09:05:39","date_gmt":"2020-03-31T02:05:39","guid":{"rendered":"http:\/\/huib.hueuni.edu.vn\/?p=7584"},"modified":"2020-03-31T09:20:41","modified_gmt":"2020-03-31T02:20:41","slug":"viable-vaccine-candidate-for-covid-19-developed-using-proprietary-plant-based-technology","status":"publish","type":"post","link":"https:\/\/huib.hueuni.edu.vn\/en\/viable-vaccine-candidate-for-covid-19-developed-using-proprietary-plant-based-technology\/","title":{"rendered":"Viable vaccine candidate for COVID-19 developed using proprietary plant-based technology"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Canadian biopharmaceutical company Medicago announced that it has successfully produced a Virus-Like Particle (VLP) of the coronavirus 20 days after obtaining the SARS-CoV-2 (the virus causing the COVID-19 disease) genetic sequence. Medicago produced the VLP using\u00a0proprietary plant-based technology. The production of the VLP is the first step in developing a vaccine for COVID-19 which will now undergo preclinical testing for safety and efficacy.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Medicago was able to produce the VLP fast using plant-based technology, a proprietary potential alternative to traditional egg-based production systems. Traditional vaccine production requires using a lot of eggs. However, this practice is not only expensive but also takes a long time and is far from perfect.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Medicago does not work with a live virus but uses plants. Their technology inserts a genetic sequence into Agrobacterium, a soil bacterium, which is taken up by plants. The plant begins to produce the protein that can then be used as a vaccine. If the virus begins to mutate, as is expected for COVID-19, they can just update the production using new plants.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">&#8220;That&#8217;s the difference between us and egg-based methods,&#8221; Medicago CEO Bruce Clark said. &#8220;We go directly to producing the vaccine or the antibody without having to propagate the virus.&#8221; Using plants and genetically engineered Agrobacterium works faster than eggs also makes the vaccine much easier to produce at scale.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-7582\" src=\"http:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1.jpg\" alt=\"\" width=\"732\" height=\"518\" srcset=\"https:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1.jpg 732w, https:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1-300x212.jpg 300w, https:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1-206x146.jpg 206w, https:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1-50x35.jpg 50w, https:\/\/huib.hueuni.edu.vn\/wp-content\/uploads\/2020\/03\/1.f-1-106x75.jpg 106w\" sizes=\"auto, (max-width: 732px) 100vw, 732px\" \/><\/p>\n<p style=\"text-align: center;\">(Source:\u00a0http:\/\/www.isaaa.org\/kc\/cropbiotechupdate\/article\/default.asp?ID=18028)<\/p>\n<p style=\"text-align: right;\"><em>Original published by ISAAA with slight modification<\/em><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Canadian biopharmaceutical company Medicago announced that it has successfully produced a Virus-Like Particle (VLP) of the coronavirus 20<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":3,"featured_media":7582,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67],"tags":[163,162],"class_list":["post-7584","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-technology","tag-hue-university","tag-institute-of-biotechnology"],"_links":{"self":[{"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/posts\/7584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/comments?post=7584"}],"version-history":[{"count":0,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/posts\/7584\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/media\/7582"}],"wp:attachment":[{"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/media?parent=7584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/categories?post=7584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/huib.hueuni.edu.vn\/en\/wp-json\/wp\/v2\/tags?post=7584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}